Type 1 diabetes complications

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Detailed Information

 

Introduction

An excessive rise in blood sugar or glucose is known as “Diabetes Mellitus”. The primary form of sugar in blood is blood glucose, which also serves as the body’s primary energy source. In addition to being produced in the muscles and liver, glucose is obtained via diet. All of the body’s cells receive glucose from the blood to utilize as fuel.

The hormone known as insulin, which transports glucose to every cell in the body, is released into the circulation by the pancreas, an organ situated between the stomach and the spine. When the pancreas produces insufficient insulin or insulin that is not functioning properly, glucose remains in the bloodstream instead of entering cells. Diabetes can be brought on by excessive blood glucose levels. Diabetes can affect people of any age or gender. Diabetes occurs in three basic types: Type 1, Type 2, and Gestational diabetes.

 

Type 1 diabetes:

Although it can occur in adults as well, type 1 diabetes, often known as juvenile diabetes, primarily affects young people.  Due to an immune system attack and subsequent destruction of the insulin-producing cells (pancreatic beta cells), type 1 diabetes results in insufficient or nonexistent insulin production. You won’t get diabetes if you eat too much sugar, despite popular belief. The immune system of a person with Type 1 diabetes attacks the beta cells in their body, which produce insulin, which is how the disease began. Monogenic diabetes is the term for a subset of rare types of diabetes caused by mutations or alterations in a single gene. The two primary types of monogenic diabetes are Maturity-Onset Diabetes of the Young (MODY) and Neonatal Diabetes Mellitus (NDM).

Before the age of six months, diabetes is more likely to be non-diabetic diabetes mellitus (NDM) than autoimmune Type 1 Diabetes Mellitus (T1DM). MODY refers to a class of hereditary autosomal-dominant conditions characterized by early-onset, usually moderate hyperglycemia (high blood sugar). Rather than insulin resistance, it is the consequence of beta-cell malfunction. MODY is associated with mutations in a minimum of eight genes. There is an older group with the slower onset disease in addition to the typical young individuals with acute onset T1DM. They may appear to have Type 2 Diabetes Mellitus (T2DM) in middle age, but tests for the anti-glutamic acid decarboxylase (GAD) antibody show indications of autoimmunity. Eventually, they develop an insulin-dependent lifestyle. This condition is known as Adult Latent Autoimmune Diabetes (LADA). 

 

Complications of type 1 diabetes

Complications from diabetes have been shown to significantly raise health care expenditures for both treating and managing the disease as well as increasing morbidity and mortality. Diabetic patients who have out-of-range diabetes treatment and higher long-term blood glucose levels are more likely to experience microvascular and macrovascular problems.

Blood glucose levels that are too high over time can lead to a number of problems, including:

  • Diseases of the eyes caused by alterations in fluid levels, tissue edema, and injury to the blood vessels in the eyes
  • Foot issues brought on by nerve damage and decreased blood flow to your foot
  • Gum disease and other dental issues, as harmful bacteria are encouraged to proliferate in your mouth by a high blood sugar level in your saliva. Food particles and bacteria interact to create plaque, a soft, sticky film. Eating foods high in sugar or carbohydrate can also cause plaque. Certain kinds of plaque lead to foul breath and gum disease. Cavities and tooth decay are caused by other types.
  • Damage to your blood vessels and the nerves that regulate your heart and blood vessels can result in heart disease and stroke.
  • Renal disease brought on by harm to the kidneys’ blood arteries. Diabetes frequently results in elevated blood pressure. That could also be bad for your kidneys.
  • Damage to the nerves and the tiny blood arteries that supply your nerves with oxygen and nutrients might result in nerve issues (diabetic neuropathy).
  • Nerve injury and decreased blood supply to the genitalia and bladder can lead to sexual and urinary issues.
  • Disorders of the skin, some of which are brought on by modifications to the small blood vessels and poor circulation. It is also more common for people with diabetes to get infections, particularly skin infections.

Additionally, acute hyperglycemia emergencies can be brought on by high blood glucose levels. These emergencies consist of:

  • The most common cause of ketoacidosis, a potentially fatal condition marked by hyperglycemia and elevated blood acid (ketone) levels, is type 1 diabetes.
  • Hyperosmolarity is a condition that causes the body to lose water from its organs. It is marked by prolonged hyperglycemia without ketoacidosis and severe dehydration.

 

Management of diabetes

Type 1 diabetes is a complicated illness that needs to be managed on a daily basis with effort and preparation. Here are some tips to help you effectively manage your Type 1 diabetes:

Check your blood sugar frequently: Using a continuous glucose monitor (CGM) or a glucometer to check your blood sugar is essential for managing diabetes and avoiding complications. If nothing else, make an effort to monitor your blood sugar levels before bed and after meals. Treating high blood sugar as soon as feasible is crucial.

Regularly take your insulin and other medications: Pay attention to the directions provided by your healthcare practitioner when taking your insulin and any additional drugs, if any.

See your endocrinologist frequently: To ensure that your Type 1 diabetes treatment plan is effective, it’s critical to see your endocrinologist frequently. Don’t be hesitant to pose targeted queries to them.

See your eye doctor and all of your other providers on a regular basis. Complications from type 1 diabetes can affect many parts of your body, but particularly your eyes. It’s crucial to visit your ophthalmologist (eye doctor) at least once a year so they can examine your eyes.

Plan ahead for a sick day: Consult your endocrinologist about self-care and managing your diabetes during illness. Diabetes-related ketoacidosis (DKA) can be brought on by illness, so it’s critical to be prepared by knowing what to do if you become ill in advance.

Stay educated: Never be reluctant to inquire about Type 1 diabetes with your healthcare physician. Your chances of leading a healthy life and avoiding problems from Type 1 diabetes increase with your level of knowledge about the disease and how to manage it.

Find a community: Making online or in-person connections with other Type 1 diabetics can make you feel less isolated while managing your condition.

Ensure your emotional well-being: Compared to people without diabetes, people with diabetes have a two to three times higher risk of depression and a 20% higher chance of receiving an anxiety diagnosis. Having a chronic illness that needs ongoing care can be very demanding. In the event that you exhibit symptoms of depression, it is imperative that you consult a mental health expert. 

 

Conclusion

Four daily actions can help blood glucose levels remain within the desired range:

  1. Stick to a balanced diet.
  2. Engage in physical activity.

III. Regulate the dosage of insulin.

  1. Monitor diabetes.

At first, these tasks could seem overwhelming. Make minor adjustments until completing these actions becomes a regular part of your day.

To prevent hypoglycemia, learn to balance your insulin dosage with each meal and physical activity. Establish a goal range for your blood sugar and raise your HbA1c (keep it between 6% and 7%). Take part in running events and diabetic camps to network with other Type 1 diabetics and gain insight from their experiences. Stay positive, do yoga, and meditate. People can resume their normal lives and no longer have to fear diabetic consequences once they have learnt how to manage their diabetes.